| East Michigan University | Ypsilanti | MI |
| Eaton | Saginaw | MI |
| Eaton Foundry | Vassar | MI |
| Eaton Yale & Towne | Vassar | MI |
| Ecorse Steel Treating | Ecorse | MI |
| Ectrans | Brighton | MI |
| Eddy Paper | Three Rivers | MI |
| Eddy Paper | White Pigeon | MI |
| Edison Electric Illuminating | Detroit | MI |
| Edison Institute | Dearborn | MI |
| Edison Light & Fuel | Grand Rapids | MI |
| Edmund & Jones | Detroit | MI |
| Edward W. Duffy & Company | Detroit | MI |
| Egyptian Portland Cement | Detroit | MI |
| Egyptian Portland Cement | Fenton | MI |
| E.H. Dyer & Company | Blissfield | MI |
| Eisenhower High School | Saginaw | MI |
| E Jackson High School | Jackson | MI |
| E.J. Kohn & Associates | Stevensville | MI |
| E J Kulas | River Rouge | MI |
| Eldred Mill | Jackson | MI |
| Electric Autolite | Bay City | MI |
| Electric Autolite | Port Huron | MI |
| Electric Light & Power | Grand Rapids | MI |
| Electric Light & Water Works | Charlevoix | MI |
| Elementary Boulevard School | Grand Rapids | MI |
| Elementary Boulevard School | Lansing | MI |
| Elf Atochem | Riverview | MI |
| Elf Atochem | Wyandotte | MI |
| Elk Cement & Lime | Elk Rapids | MI |
| Elk Rapids Portland Cement | Elk Rapids | MI |
| Eloise General Hospital | Wayne | MI |
| Eloise General Hospital | Westland | MI |
| Empire Iron Mining | Palmer | MI |
| Empire Iron Mining | Negaunee | MI |
| Engineered Furnaces | Troy | MI |
| Engineered Heat Treat | Madison Heights | MI |
| Enterprise Machine | Detroit | MI |
| E.N. Voight Brewing | Detroit | MI |
| E.P. Decker | Detroit | MI |
| Erie City Boiler | Lawrence | MI |
| Erie City Energy Div Zurns | Midland | MI |
| Erie Power House | Erie | MI |
| Erie Senior High School | Erie | MI |
| Escanaba Paper | Groos | MI |
| Essex International | Three Rivers | MI |
| Essex Wire | Coldwater | MI |
| Essex Wire & Sheffield Car | Three Rivers | MI |
| Estate Of P.D. Beckwith | Dowagiac | MI |
| Ethyl | Detroit | MI |
